A Type of Drug-Food Interaction
September 28th 2009 06:38
A patient comes in with the following details:
•Has been suffering from depression
•Tried several anti-depressants but nothing worked for her, except for Iproniazid
oIproniazid is a MAO inhibitor, can be considered as a last line for depression management
oIproniazid then was a new drug and side effects are yet to be discovered.
oHer doctor asked her to notify him in case of any unusual effects
•Condition improved and was able to return to usual life
•Hosted a wine and cheese party during which she had severe headache
•In the hospital BP is at 230/160 mmHg
•MD administered phentolamine ( non-selective Alpha receptor antagonist) to address HPN
Then we ask the following:
Why Did the Patient Had Headache and Hypertension Crisis Upon Intake of Wine and Cheese?
Patient was given Phentolamine. How does it act? Why was it useful in this case?
Why didn’t the physician use a Beta-adrenoceptor antagonist to treat the condition?
to be continued...
•Has been suffering from depression
•Tried several anti-depressants but nothing worked for her, except for Iproniazid
oIproniazid is a MAO inhibitor, can be considered as a last line for depression management
oIproniazid then was a new drug and side effects are yet to be discovered.
oHer doctor asked her to notify him in case of any unusual effects
•Condition improved and was able to return to usual life
•Hosted a wine and cheese party during which she had severe headache
•In the hospital BP is at 230/160 mmHg
Then we ask the following:
Why Did the Patient Had Headache and Hypertension Crisis Upon Intake of Wine and Cheese?
Patient was given Phentolamine. How does it act? Why was it useful in this case?
Why didn’t the physician use a Beta-adrenoceptor antagonist to treat the condition?
to be continued...
| 42 |
| Vote |
