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The Structural and the Biochemical Changes in Alzheimer’s Disease

February 25th 2009 03:24
Alzheimer’s Disease and Dementia

One of the most common causes of dementia is Alzheimer’s disease. As early as this point, we have to understand that Alzheimer’s disease is different from dementia. Others include Parkinson’s disease, drug intoxication, and vascular diseases.

Dementia is an acquired deterioration in cognitive abilities that impairs the successful performance of activities of daily living. Memory is the most common cognitive ability lost with dementia. In addition to memory, other mental faculties are also affected such as language, visuospatial ability, calculation, judgment, and problem solving. Neuropsychiatric and social deficits develop in many dementia syndromes resulting in depression, withdrawal, hallucinations, delusions, agitations, insomnia, and disinhibition.


In Alzheimer’s disease, involvement of the above symptoms depends on the disease progression and the extent of damage among the brain structures.

Atrophy of the structures corresponding to the above functions usually is the feature of Alzheimer’s disease.
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